37580

3,4-Dihydroxybenzoic acid

≥97.0% (T)

Manufacturer: Sigma Aldrich

CAS Number: 99-50-3

Synonym(S): Protocatechuic acid

Select a Size

Pack Size SKU Availability Price
25 G 37580-25-G In Stock ₹ 6,765.63
100 G 37580-100-G In Stock ₹ 16,789.58

37580 - 25 G

₹ 6,765.63

In Stock

Quantity

1

Base Price: ₹ 6,765.63

GST (18%): ₹ 1,217.813

Total Price: ₹ 7,983.443

Quality Level

200

Assay

≥97.0% (T)

mp

197-200 °C (dec.) (lit.)

SMILES string

OC(=O)c1ccc(O)c(O)c1

InChI

1S/C7H6O4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H,(H,10,11)

InChI key

YQUVCSBJEUQKSH-UHFFFAOYSA-N

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Description

  • General description: 3,4-Dihydroxybenzoic acid is reported as dietery polyphenol.[1] Antiviral activity of 3,4-dihydroxybenzoic acid (protocatechuic acid, PCA) against a virulent H9N2 strain in a mouse model is reported.[2] Cytotoxic effects of PCA on 3 non-small cell lung cancer (NSCLC) cell lines, A549, H3255, and Calu-6 cell lines is reported.[3] PCA is reported to prevent the carcinogenesis or antitumor growth in vivo. Signaling pathway involved in PCA-induced apoptosis in human gastric adenocarcinoma (AGS) cells is reported.[4] The oxidation of 3,4-dihydroxybenzoic acid by H2O2 in aqueous/goethite slurry at varying operating conditions (catalyst load, temperature, pH, substrate and hydrogen peroxide starting concentration) is investigated.[5]
  • Application: 3,4-Dihydroxybenzoic acid is suitable for use in a study to investigate the effect of 4-coumaric and 3,4-dihydroxybenzoic acid on the basal oxidative DNA damage of rat colonic mucosa in vivo.[1] It may be used in the derivatization of chitosan resin.[6]
  • Biochem/physiol Actions: Chemopreventive in several animal models of carcinogenesis. Blocks cell proliferation in the post-initiation phase.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves