W4394

Withaferin A

≥95% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 5119-48-2

Synonym(S): 5,6-Epoxy-4,27-dihydroxy-1-oxowitha-2,24-dienolide, Withaferine A

Select a Size

Pack Size SKU Availability Price
5 MG W4394-5-MG In Stock ₹ 62,568.50

W4394 - 5 MG

₹ 62,568.50

In Stock

Quantity

1

Base Price: ₹ 62,568.50

GST (18%): ₹ 11,262.33

Total Price: ₹ 73,830.83

biological source

plant (Withania somnifera)

Quality Level

200

Assay

≥95% (HPLC)

form

powder

mp

252-253 °C

functional group

epoxyketone

shipped in

ambient

storage temp.

2-8°C

SMILES string

C[C@H]([C@H]1CC(C)=C(CO)C(=O)O1)[C@H]2CC[C@H]3[C@@H]4C[C@H]5O[C@]56[C@@H](O)C=CC(=O)[C@]6(C)[C@H]4CC[C@]23C

InChI

1S/C28H38O6/c1-14-11-21(33-25(32)17(14)13-29)15(2)18-5-6-19-16-12-24-28(34-24)23(31)8-7-22(30)27(28,4)20(16)9-10-26(18,19)3/h7-8,15-16,18-21,23-24,29,31H,5-6,9-13H2,1-4H3/t15-,16-,18+,19-,20-,21+,23-,24+,26+,27-,28+/m0/s1

Other Options

Image Product Name Manufacturer Price Range
MilliporeSigma™ Calbiochem™ Withaferin A, Withania somnifera
-- --
MilliporeSigma™ Calbiochem™ Withaferin A, Withania somnifera
-- ₹ 13,904.47
MilliporeSigma™ Calbiochem™ Withaferin A, Withania somnifera
-- ₹ 48,662.53
Medchemexpress LLC HY-N2065 5mg , Withaferin A CAS:5119-48-2 Purity:>98%
-- ₹ 34,950.30
phyproof™ Withaferin A, ≥95% (HPLC), MilliporeSigma™ Supelco™
-- ₹ 60,075.00
Withaferin A, ≥95% (HPLC), MilliporeSigma™ Supelco™
-- ₹ 92,649.00
Enzo Life Sciences Withaferin A (10mg). CAS: 5119-48-2
-- ₹ 51,089.56
AdipoGen Withaferin A,Chemical. CAS: 5119-48-2
-- ₹ 7,164.50
Withaferin A
-- ₹ 74,032.18
Withaferin A
-- ₹ 81,847.83

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Description

  • Application: Withaferin A was used to treat HEK293 cells to study its effect on cystic fibrosis inflammation.[1]
  • Biochem/physiol Actions: Withaferin A is a steroidal lactone that is isolated from the plant Withania somnifera. It has potent anti-inflammatory properties as it inhibits the activation of NF-κ B signaling pathway.[2] The anti-tumor activity of Withaferin A is due to its ability to alter cytoskeletal architecture by binding annexin II and disrupting F actin cross-links.[3] Withaferin A also inhibits angiogenesis by binding to vimentin and F-actin.[4]
  • Preparation Note: Withaferin A yields a clear, colorless solution in methanol at 1 mg/ml.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

438.8 °F

Flash Point(C)

226 °C