1357056

Leflunomide Related Compound B

United States Pharmacopeia (USP) Reference Standard

Manufacturer: Sigma Aldrich

CAS Number: 108605-62-5

Synonym(S): 2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide

Select a Size

Pack Size SKU Availability Price
20 MG 1357056-20-MG In Stock ₹ 1,42,662.68

1357056 - 20 MG

₹ 1,42,662.68

In Stock

Quantity

1

Base Price: ₹ 1,42,662.68

GST (18%): ₹ 25,679.282

Total Price: ₹ 1,68,341.962

grade

pharmaceutical primary standard

API family

leflunomide

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O=C(/C(C#N)=C(O)/C)NC1=CC=C(C(F)(F)F)C=C1

InChI

1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-

InChI key

UTNUDOFZCWSZMS-YFHOEESVSA-N

Gene Information

human ... DHODH(1723)

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Description

  • General description: Leflunomide Related Compound B (2-Cyano-3-hydroxy-N-(4-trifluoromethylphenyl)crotonamide is a malononitrilamide which is a water soluble metabolite of Leflunomide. It is considered as a noncompetitive inhibitor of dihydro-orotate dehydrogensae. This metabolite has been reported to initially target activated lymphocytes.[1]
  • Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
  • Other Notes: Sales restrictions may apply.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable