19-935-0

Halofuginone hydrobromide

Manufacturer: R&D Systems

CAS Number: 64924-67-0

Select a Size

Pack Size SKU Availability Price
Each of 1 19-935-0-Each-of-1 In Stock ₹ 16,892.20

19-935-0 - Each of 1

₹ 16,892.20

In Stock

Quantity

1

Base Price: ₹ 16,892.20

GST (18%): ₹ 3,040.596

Total Price: ₹ 19,932.796

Chemical Name or Material

(2R*,3S*)-7-Bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]-4-3H-quinazolinone hydrobromide

Assay Percent Range

>98%

Molecular Formula

C16H17BrClN3O3.HBr

CAS

64924-67-0

Quantity

50 mg

Formula Weight

Observed MW: 495.59

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Description

  • Halofuginone hydrobromide is a high affinity competitive prolyl-tRNA synthetase inhibitor (Ki = 18.3 nM)
  • Blocks expression of MMP2
  • Inhibits ECM invasion in vitro and lung metastasis by bladder cancer cells in mice
  • Inhibits the development of Th17-driven autoimmunity in a mouse model of multiple sclerosis by activating the amino acid response (AAR) pathway
  • Also antiparasitic.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C