70-441-00

Tocris Bioscience™ (+/-)-a-Lipoamide, Liquid-Liquid Phase Separated

Manufacturer: Tocris Bioscience™

CAS Number: 1077-28-7

Select a Size

Pack Size SKU Availability Price
Each of 1 70-441-00-Each-of-1 In Stock ₹ 10,220.76

70-441-00 - Each of 1

₹ 10,220.76

In Stock

Quantity

1

Base Price: ₹ 10,220.76

GST (18%): ₹ 1,839.737

Total Price: ₹ 12,060.497

Chemical Name or Material

1,2-Dithiolane-3-pentanoic acid

Quantity

100 mg

Purity

98%

CAS

1077-28-7

Molecular Formula

C8H14O2S2

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Description

  • (±)-α-Lipoic acid (ALA) is a liquid-liquid phase separated condensate modifier
  • Reduces stress granule formation in HeLa cells
  • Also stimulates mitochondrial biogenesis in 3T3-L1 adipocytes
  • Prevents dieback of FUS mutant motor neurons in culture and reverses motor defects in D
  • melanogaster expressing mutated human FUS
  • (±)-α-Lipoic acid is also an antixocidant
  • In hematopoietic stem cells (HSC) (±)-α-Lipoic acid reduces levels of reactive oxygen species (ROS) and inhibits apoptosis
  • It also promotes the generation of hematopoietic stem/progenitor cells from hPSCs in vitro and maintenance of functional cord blood HSCs ex vivo .