7139269

Terbinafine hydrochloride

Selective TASK3 activator

Manufacturer: Fischer Scientific

CAS Number: 78628-80-5

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CAS

78628-80-5

Molecular Formula

C21H25N.HCl

Purity

98%

Synonym

N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine hydrochloride

Formula Weight

327.89

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Description

  • Selective TASK3 activator (pEC50 = 6.2)
  • Exhibits >10-fold selectivity for TASK3 over TREK2, TRESK, THIK1 and TASK2
  • Also inhibits TWIK1 (pIC50 = 5.69)
  • Also antifungal; inhibits fungal sterol biosynthesis by inhibition of squalene epoxidase.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C