73-425-0

Tocris Bioscience™ Emetine dihydrochloride

Manufacturer: Tocris Bioscience™

CAS Number: 316-42-7

Select a Size

Pack Size SKU Availability Price
Each of 1 73-425-0-Each-of-1 In Stock ₹ 13,866.20

73-425-0 - Each of 1

₹ 13,866.20

In Stock

Quantity

1

Base Price: ₹ 13,866.20

GST (18%): ₹ 2,495.916

Total Price: ₹ 16,362.116

Chemical Name or Material

(2 S,3 R,11 bS)-3-Ethyl-1,3,4,6,7,11 b-hexahydro-9,10-dimethoxy-2-[[(1 R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-2 H-benzo[a]quinolizine dihydrochloride

Quantity

50 mg

Molecular Formula

C29H40N2O40.2 HCl

CAS

316-42-7

Target

RNA/DNA Polymerase Inhibitors

Purity

0.98

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Description

  • Emetine is a RNA polymerase inhibitor
  • It inhibits SARS-CoV-2 replication (EC50 = 460 nM) and in combination with Remdesivir (Cat
  • No.7226) synergistically inhibits the viral yield of SARS-CoV-2 by 64.9%
  • Emetine attenuates hCoV-OC43, hCoV-NL43, SARS-CoV, MERS-CoV, and MHV-A59 in vitro with EC50 values in the low micromolar range
  • It also inhibits replication of a broad range of RNA and DNA viruses, including influenza, ebolavirus and HIV-1
  • Emetine potently inhibits ZIKV replication in vitro (IC50 = 52.9 nm) and suppresses ZIKV viral load in vivo
  • Anti-inflammatory, antiviral, antimalarial, antibacterial and anti-amebic.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C