94687

Everolimus

analytical standard

Manufacturer: Supelco

CAS Number: 159351-69-6

Synonym(S): 42-O-(2-Hydroxyethyl)rapamycin

Select a Size

Pack Size SKU Availability Price
10 MG 94687-10-MG In Stock ₹ 18,261.78

94687 - 10 MG

₹ 18,261.78

In Stock

Quantity

1

Base Price: ₹ 18,261.78

GST (18%): ₹ 3,287.12

Total Price: ₹ 21,548.90

grade

analytical standard

Quality Level

100

Assay

≥75.0% (qNMR)

shelf life

limited shelf life, expiry date on the label

application(s)

clinical testing

format

neat

storage temp.

−20°C

SMILES string

O=C(C([C@@]1(O)[C@H](C)CC[C@](C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C2=O)([H])O1)=O)N3[C@H](C(O[C@@]([C@@H](C[C@@]4([H])C[C@@H](OC)[C@H](OCCO)CC4)C)([H])CC([C@H](C)/C=C(C)/[C@@H](O)[C@H]2OC)=O)=O)CCCC3

InChI

1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1

InChI key

HKVAMNSJSFKALM-GKUWKFKPSA-N

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Description

  • General description: Everolimus (RAD001), a derivative of rapamycin,[1] is commonly used as a drug for the inhibition of the mTOR pathway, affecting tumor cell division and angiogenesis.[2]
  • Application: Everolimus may be used as a standard in the following clinical studies: Investigation of its glucose-dependent growth-inhibitory property in breast cancer cell lines.[3] Evaluate its possible antiproliferative effects in human bronchial carcinoids in primary culture.[4]

SAFETY INFORMATION

Pictograms

GHS08,GHS09

Signal Word

Warning

Hazard Statements

H351,H361fd,H373,H410

Precautionary Statements

P202 - P260 - P273 - P280 - P308 + P313 - P391

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Repr. 2 - STOT RE 2

Target Organs

Kidney,Testes

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable