G8503

18α-Glycyrrhetinic acid

≥95%

Manufacturer: Sigma Aldrich

CAS Number: 1449-05-4

Synonym(S): 18α-Glycyrrhetic acid, 18-Isoglycyrrhetinic acid, 3β-Hydroxy-11-oxo-18α,20β-olean-12-en-29-oic acid

Select a Size

Pack Size SKU Availability Price
250 MG G8503-250-MG In Stock ₹ 10,976.55
1 G G8503-1-G In Stock ₹ 32,377.58

G8503 - 250 MG

₹ 10,976.55

In Stock

Quantity

1

Base Price: ₹ 10,976.55

GST (18%): ₹ 1,975.779

Total Price: ₹ 12,952.329

Quality Level

100

Assay

≥95%

SMILES string

[H][C@]12C[C@](C)(CC[C@]1(C)CC[C@]3(C)C2=CC(=O)C4[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]34C)C(O)=O

InChI

1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21+,22+,23-,26-,27+,28+,29-,30-/m1/s1

InChI key

MPDGHEJMBKOTSU-PMTKVOBESA-N

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Description

  • General description: 18α-Glycyrrhetinic acid (18α-GA) is a bioactive triterpenoid found in licorice.[1] It shows selective inhibition of 11-HSD1 (11-hydroxysteroid dehydrogenase 1).[2] It also shows anti-proliferative and apoptotic effect on hepatic stellate cells (HSCs).[3]
  • Application: 18α-Glycyrrhetinic acid may be used to synthesize:[4]3-keto-18α-glycyrrhetinic acid methyl esters of 18α-glycyrrhetinic acidmethyl esters of 3-keto-18α-glycyrrhetinic acid

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves