I4125
Inosine
≥99% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 58-63-9
Synonym(S): (−)-Inosine, Hypoxanthine 9-β-D-ribofuranoside
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 G | I4125-5-G | In Stock | ₹ 2,220.00 |
| 1 G | I4125-1-G | In Stock | ₹ 2,814.50 |
| 10 G | I4125-10-G | In Stock | ₹ 3,886.18 |
| 25 G | I4125-25-G | In Stock | ₹ 6,159.43 |
| 100 G | I4125-100-G | In Stock | ₹ 22,147.95 |
I4125 - 5 G
In Stock
Quantity
1
Base Price: ₹ 2,220.00
GST (18%): ₹ 399.60
Total Price: ₹ 2,619.60
Quality Level
200
Assay
≥99% (HPLC)
mp
222-226 °C (dec.) (lit.)
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3C(=O)NC=Nc23
InChI
1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7-,10-/m1/s1
InChI key
UGQMRVRMYYASKQ-KQYNXXCUSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Apexbio Technology LLC Homodimer binding to FKBP. AP1903 10mM (in 1mL DMSO). 58-63-9. MFCD22689457 | -- | ₹ 46,280.00 | ||
Cambridge Isotope Laboratories Inosine (15N4) | 58-63-9 | MFCD00066770 | 0.01 g | -- | ₹ 62,769.92 | ||
Adenosine Impurity G | -- | ₹ 38,223.08 | ||
Inosine | -- | ₹ 979.00 - ₹ 4,717.00 | ||
58-63-9 | Inosine | -- | ₹ 356.00 - ₹ 2,136.00 |
Description
- General description: Inosine is a non-canonical nucleotide majorly present as monophosphate. It has ability to base pair with deoxythymidine, deoxyadenosine and deoxyguanosine.[1] Incorporation of inosine in place of guanine modulates translational events.[2] Inosine has antioxidant, anti-inflammatory and neuroprotective functionality. Inosine is prescribed as a therapeutic supplement for nerve injury, inflammation and oxidative stress.[3] It modulates biological processes through adenosine receptors. Its enhances neurite outgrowth in depressive disorders via adenosine receptors.[4] Inosine is also used for treating sepsis in infections.[5]
- Application: Inosine has been used:as a medium supplement in nucleotide rescue experiments in pancreatic cancer cell lines.[6]as a component in holidic (synthetic) medium and in larval two-choice preference assay.[7]as a reference standard in mass spectroscopy.[8]
- Biochem/physiol Actions: Inosine is a potent stimulator of nerve growth factor (NGF) induced neurite outgrowth. The elevated levels of inosine in brain following injury are associated with the increased expression proteins related to axonal regeneration and growth. Mice given inosine demonstrated enhanced recovery of fine motor control following ischemic brain damage. Inosine may be used in studies of the process A-to-I RNA editing.
SAFETY INFORMATION
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves