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SDS
PHR1145

Doxycycline hyclate

Pharmaceutical Secondary Standard; Certified Reference Material

Manufacturer: Supelco

CAS Number: 24390-14-5

Synonym(S): Doxycycline hydrochloride hemiethanolate hemihydrate

Select a Size

Pack Size SKU Availability Price
1 G PHR1145-1-G In Stock ₹ 11,810.08

PHR1145 - 1 G

₹ 11,810.08

In Stock

Quantity

1

Base Price: ₹ 11,810.08

GST (18%): ₹ 2,125.814

Total Price: ₹ 13,935.894

grade

certified reference materialpharmaceutical secondary standard

Quality Level

300

Agency

traceable to BP 780traceable to Ph. Eur. D3000000traceable to USP 1226003

API family

doxycycline

CofA

current certificate can be downloaded

technique(s)

HPLC: suitablegas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

-10 to -25°C

SMILES string

Cl[H].Cl[H].[H]O[H].CCO.C[C@@H]1C2[C@H](O)C3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14.C[C@@H]5C6[C@H](O)C7[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]7(O)C(O)=C6C(=O)c8c(O)cccc58

Description

  • General description: Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.Doxycycline, the semi-synthetic analog of tetracycline, is a broad-spectrum antibiotic employed in medicine and veterinary applications, is known for its action against a huge range of gram positive and gram negative bacteria. It is prescribed against infections spread by rickettsiae, mycoplasmas and chlamydiae.[1][2]
  • Application: Doxycycline hyclate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and biological samples[2] by various chromatography[1][3][2] and spectrophotometric[4] techniques.
  • Biochem/physiol Actions: Mode of Action: Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi.Activity Spectrum: Effective against a broad spectrum inhibitor of matrix metalloproteinases in vivo.
  • Analysis Note: These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
  • Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
  • Footnote: To see an example of a Certificate of Analysis for this material enter LRAC0269 in the slot below. This is an example certificate only and may not be the lot that you receive.
  • Recommended products: Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

SAFETY INFORMATION

Pictograms

GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335,H361fd,H412

Precautionary Statements

P202 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable