17-614-MI

MilliporeSigma™ Upstate™ Trimethyl-Histone H3 (Lys4)α, Rabbit Monoclonal, ChIP Validated Antibody and Primer Set

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 17-614-MI-Each-of-1 In Stock ₹ 55,714.89

17-614-MI - Each of 1

₹ 55,714.89

In Stock

Quantity

1

Base Price: ₹ 55,714.89

GST (18%): ₹ 10,028.68

Total Price: ₹ 65,743.57

Antigen

Trimethyl-Histone H3 (Lys4)α

Classification

Monoclonal

Formulation

Anti-Trimethyl-Histone H3 (Lys4) recombin-ant rabbit monoclonal IgG. One vial containing 75μL of protein A purified rabbit IgG in storage buffer (0.1M Tris-Glycine pH 7.4, 0.15M NaCl, 0.05% NaN3, with the addition of 40% glycerol.Normal Rabbit IgG. One vial containing 75μL of normal rabbit IgG.Control Primers. One vial containing 75μL of 5μM of each primer specific for human GAPDH. FOR: TAC TAG CGG TTT TAC GGG CG REV: TCG AAC AGG AGG AGC AGA GAG CGA

Gene Symbols

H3F3A, H3F3B, H3F3

Immunogen

The trimethyl-histone H3 (Lys4) antibody is made against a BSA-conjugated, synthetic peptide containing the sequence …RT[me3K]QT… in which me3K corresponds to trimethyl-lysine 4 of human histone H3

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Trimethyl-Histone H3 (Lys4)

Target Species

Human, Mammalia, Mouse

Form

Purified

Applications

ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot

Conjugate

Unconjugated

Gene Accession No.

Q66I33

Host Species

Rabbit

Quantity

25 Assays

Research Discipline

Epigenetics, Nuclear Function

Gene ID (Entrez)

NM_003493

Includes

Trimethyl-Histone H3 (Lys4) ChIP validated Antibody and Primer set including the ChIP-grade antibody and the specific control PCR primers used for chromatin immunoprecipitation of H3K4Me3.

Content And Storage

−20°C for one year from date of shipment

Isotype

IgG

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Description

  • Specifically detects Trimethyl-Histone H3 (Lys4)α Clone: in Human, Mammalia, Mouse samples, and it is validated for ChIP, ChIP-seq, Western Blotting The methylation of histones can occur on two different residues: arginine or lysine
  • Histone methylation can be associated with transcriptional activation or repression, depending on the methylated residue
  • Lysine 4 of histone H3 can be mono-, di- or trimethylated by different histone methyltransferases (HMTs) such as SET1 or ASH1
  • Methylation of Lys4 is often associated with transcriptional activation
  • The demethylase LSD1 is able to demethylate histone H3 Lys4.