01-670-512
beta Synuclein Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-670-512-Each-of-1 | In Stock | ₹ 48,905.50 |
01-670-512 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
beta Synuclein
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SNCB
Gene Alias
AI838531; betaSYN; beta-synuclein; Phosphoneuroprotein 14; PNP 14; Sncb; synuclein beta; synuclein, beta
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Frozen), Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with no preservative
Gene Accession No.
Q16143, Q63754
Gene Symbols
SNCB
Immunogen
Synthetic peptide corresponding to residues I(108) E P L M E P E G S Y E D P P Q E(125) of human beta synuclein protein.
Regulatory Status
RUO
Gene ID (Entrez)
113893, 6620
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
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Description
- Reconstitute in 100 μL of sterile water
- Centrifuge to remove any insoluble material
- After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent
- Glycerol (1:1) may be added for an additional stability
- Avoid repetitive freeze/thaw cycles
- Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals
- In vertebrates they are encoded by three different genes
- Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer
- In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid
- In PD, an alpha synuclein accumulates in Lewy bodies
- An allele of alpha synuclein has been linked to many familial cases of PD
- In breast cancer increased expression of gamma synuclein correlates with the disease progression
- Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.