TACR3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-670-562-Each-of-1 | In Stock | ₹ 48,905.50 |
01-670-562 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
TACR3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Tacr3
Gene Alias
G protein-coupled receptor; HH11; neurokinin 3 receptor; Neurokinin B; neurokinin B receptor; neurokinin beta receptor; neuromedin K receptor; Neuromedin K receptor (Neurokinin B/Tachikin 3); neuromedin-K receptor; Nk3 receptor; NK-3 receptor; NK3R; NK-3R; NK3R TAC3R; Nkr; Nmkr; Nmk-r; TAC3R; TAC3RL; tachikin receptor 3; tachykinin receptor 3; Tacr3
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Concentration
Conc. Not Determined
Formulation
whole serum with no preservative
Gene Accession No.
P16177
Gene Symbols
Tacr3
Immunogen
Synthetic peptide corresponding to the C-terminal residues A(434) S T T S S F I S S P Y T S V D E Y S(452) of rat NK-3 receptor protein.
Regulatory Status
RUO
Gene ID (Entrez)
24808
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Lyophilized
Related Products
Description
- Reconstitute in 100 μL of sterile water
- Centrifuge to remove any insoluble material
- After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent
- Glycerol (1:1) may be added for an additional stability
- Avoid repetitive freeze/thaw cycles
- The tachykinins are a family of small peptides that include the neurotransmitters substance P, neurokinin A, and neurokinin B, which can act on three related but distinct seven transmembrane G-proteins coupled receptors, albeit at different concentrations
- The NK-3 receptor (NK3R) has greatest affinity for neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei
- Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system
- It is likely these signals lead to the release of vasopressin and oxytocin into the circulation
- NK3R may be involved in learning and memory as mice lacking this gene expressed cognitive deficits compared to normal mice
- Although it has been suggested that NK3R plays a role in the regulation of vagal afferent relay neurons, it is likely that these receptors are activated by substance P or neurokinin A, as the airway nerves do not express neurokinin B.