CD8/CD28 Antibody Cocktail, FITC, PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-670-886-Each-of-1 | In Stock | ₹ 44,811.50 |
01-670-886 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
CD8/CD28
Classification
Cocktail
Conjugate
PE
Gene
CD28
Gene Alias
CD28; CD28 antigen; CD28 molecule; CD8; CD8 antigen, alpha polypeptide (p32); CD8 antigen, beta polypeptide 1 (p37); CD8A; CD8a molecule; CD8alpha; CD8b; CD8b molecule; CD8B1; CD8beta; LEU2; Leu-2; Leu2 T-lymphocyte antigen; LY3; LYT3; MAL; MGC138290; OKT8 T-cell antigen; p32; P37; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T8 T-cell antigen; T-cell antigen Leu2; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-cell-specific surface glycoprotein CD28; T-lymphocyte differentiation antigen T8/Leu-2; Tp44
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
925, 926, 940
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
17D8, B-23, B-23
Formulation
PBS with 0.2% carrier protein and 0.08% sodium azide
Gene Accession No.
P01732, P10747, P10966
Gene Symbols
CD28, CD8A, CD8B
Immunogen
human peripheral blood T lymphocytes and HPB-ALL T-cell line
Quantity
50 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- This antibody is a monoclonal mixture of FITC-conjugated CD8 (clone 17D8, isotype IgG1) and PE-conjugated CD28 (clone B-23, isotype IgG1)
- CD8 molecule is composed of two chains termed alpha and beta
- CD8 is found on a T cell subset of normal cytotoxic / suppressor cells which make up approximately 20 to 35 % of human peripheral blood lymphocytes
- The CD8 antigen is also detected on natural killer cells, 80% of thymocytes, on a subpopulation of 30% of peripheral blood null cells and 15 to 30% of bone marrow cells
- Human CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein
- It is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes (approximately 95% of CD4+ cells and 50% of CD8+ cells)
- Mature thymocytes exhibit higher levels of CD28 than the immature cells
- Activation of T cells results in enhanced CD28 expression
- T cell activation requires two combined signals provided by antigen presenting cells.