MRP5 Monoclonal Antibody (M5I-1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-671-089-Each-of-1 | In Stock | ₹ 62,122.00 |
01-671-089 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 62,122.00
GST (18%): ₹ 11,181.96
Total Price: ₹ 73,303.96
Antigen
MRP5
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
tissue culture supernatant with 0.7% BSA and 0.1% sodium azide
Gene Accession No.
O15440
Gene Symbols
ABCC5
Immunogen
ABCC5.
Regulatory Status
RUO
Gene ID (Entrez)
10057
Content And Storage
4°, C
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone
M5I-1
Conjugate
Unconjugated
Gene
ABCC5
Gene Alias
2900011L11Rik; ABC 33; ABC33; ABCC 5; ABCC5; Abcc5a; Abcc5b; AI132311; ATP binding cassette subfamily C member 5; ATP-binding cassette sub-family C (CFTR/MRP) member 5a; ATP-binding cassette sub-family C member 5; ATP-binding cassette, subfamily C (CFTR/MRP), member 5; ATP-binding cassette, sub-family C (CFTR/MRP), member 5; ATP-binding cassette, sub-family C (CFTR/MRP), member 5a; ATP-binding cassette, sub-family C (CFTR/MRP), member 5b; ATP-binding cassette, sub-family C, member 5; canalicular multispecific organic anion transporter C; DKFZp686C1782; EST277145; MOAT C; MOATC; MOAT-C; MRP 5; MRP5; multidrug resistance-associated protein 5; Multi-specific organic anion transporter C; pABC 11; pABC11; SMRP
Host Species
Rat
Quantity
1 mL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters
- ABC proteins transport various molecules across extra- and intra-cellular membranes
- ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)
- This protein is a member of the MRP subfamily which is involved in multi-drug resistance
- This protein functions in the cellular export of its substrate, cyclic nucleotides
- This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides
- Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine
- This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients
- Alternative splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear.