01-671-856
Factor XII Heavy chain Monoclonal Antibody (B7C9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-671-856-Each-of-1 | In Stock | ₹ 62,122.00 |
01-671-856 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 62,122.00
GST (18%): ₹ 11,181.96
Total Price: ₹ 73,303.96
Antigen
Factor XII Heavy chain
Classification
Monoclonal
Concentration
1.4 mg/mL
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
P00748
Gene Symbols
F12
Immunogen
Purified human Factor XII.
Quantity
250 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Western Blot
Clone
B7C9
Conjugate
Unconjugated
Gene
F12
Gene Alias
Beta-factor XIIa part 1; beta-factor XIIa part 2; Coagulation factor XII; coagulation factor XII (Hageman factor); coagulation factor XIIa heavy chain; Coagulation factor XIIa light chain; F12; Factor 12; factor XII; Factor12; FXII; HAE3; HAEX; HAF; Hageman factor
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
2161
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-10828 detects Factor XII heavy chain, from human samples
- MA1-10828 has been successfully used in ELISA and Western blot applications
- By Western blot, this antibody detects a ∽50 kDa band representing the non-reduced heavy chain of Factor XII from normal human plasma
- The MA1-10828 immunogen is purified human Factor XII
- Hemostasis following tissue injury involves the deployment of essential plasma procoagulants which are involved in a blood coagulation cascade leading to the formation of insoluble fibrin clots and the promotion of platelet aggregation
- Factor XII, (FXII) a blood coagulation factor, is a serum glycoprotein that participates in fibrinolysis, as well as the generation of bradykinin and angiotensin
- An enzyme of the serine protease (or serine endopeptidase) class, it activates both Factor XI and prekallikrein in the coagulation cascade
- Factor XII deficiency, a rare hereditary disorder slightly more prevalent among Asians, does not cause excessive hemorrhaging since other coagulation factors compensate for it
- Researchers have still reported Factor XII deficiency to be a risk factor for the development of arterial and venous thromboembolism
- The gene for human Factor XII maps to the very end of the long arm of the fifth chromosome (5q33-qter).