01-671-868

IGF1R alpha Monoclonal Antibody (2C8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-671-868-Each-of-1 In Stock ₹ 47,481.50

01-671-868 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

IGF1R alpha

Classification

Monoclonal

Concentration

0.6 mg/mL

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

P08069

Gene Symbols

Igf1r

Immunogen

Purified human placental IGF-1 receptors.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

2C8

Conjugate

Unconjugated

Gene

Igf1r

Gene Alias

A330103N21Rik; CD221; D930020L01; hyft; IGF-1 receptor; Igf1r; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; insulin-like growth factor 1 receptor beta subunit; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; insulin-like growth factor-I receptor; insulin-like growth factor-I receptor precursor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

3480

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA1-10855 detects IGF-1 Receptor from human samples
  • MA1-10855 has been successfully used in Western blot applications
  • The MA1-10855 immunogen is purified human placental IGF-1 receptors
  • IGF1R (Insulin-like Growth Factor1 Receptor) is a receptor tyrosine kinase that mediates actions of insulin-like growth factor 1 (IFG1)
  • It binds IGF1 with high affinity and IGF2/insulin with lower affinity
  • Activated IGF1R is involved in cell growth and survival control
  • IGF1R is crucial for tumor transformation and survial of malignant cells
  • Ligand binding activates the receptor kinase and leads to receptor autophosphorylation and tyrosines phosphorylation of multiple substrates that function as signaling adapter proteins.