Calpain S1/S2 Monoclonal Antibody (28F3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-303-Each-of-1 | In Stock | ₹ 47,481.50 |
01-674-303 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Calpain S1/S2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 3mM sodium azide; pH 7.5
Gene Accession No.
P04632, P13135, Q96L46
Gene Symbols
CAPNS1, CAPNS2
Immunogen
Human Calpain protein purified from placenta.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Bovine, Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Immunoprecipitation, Western Blot
Clone
28F3
Conjugate
Unconjugated
Gene
CAPNS2
Gene Alias
2310005G05Rik; 30K-2; calcium-activated neutral proteinase 2; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease small subunit 2; calcium-dependent protease, small subunit; calpain 2; calpain 2, (m/II) large subunit; calpain 2, large [catalytic] subunit; calpain 2, large subunit; calpain 4; calpain 4, small subunit (30K); calpain II regulatory subunit; calpain II regulatory subunit (EC 3.4.22.17); calpain large polypeptide L2; Calpain M-type; calpain regulatory subunit; Calpain small subunit 1; calpain small subunit 2; calpain, large polypeptide L2; calpain, small polypeptide; calpain, small subunit 1; calpain, small subunit 2; calpain-2 catalytic subunit; Calpain-2 large subunit; CALPAIN4; CANP; CANP 2; CANP small subunit; CANP2; CANPL2; CANPml; CANPS; Capa4; Capa-4; CAPN2; Capn4; CAPNS; CAPNS1; Capns2; CDPS; CSS1; CSS2; D7Ertd146e; M-calpain; mCANP; Millimolar-calpain
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
100300424, 281664, 826, 84290
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody specifically recognizes the 28 to 30 kD small subunit of Calpain 1 and Calpain 2 (mu calpain and m calpain)
- It recognizes both native and denatured protein in ELISA, Western Blot and Immunoprecipitation
- The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems
- Both m-calpain (calpain II) and m-calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit
- Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names
- Whereas m-calpain requires millimolar (mM) levels of calcium, m-calpain is active at micromolar (mM) concentrations of Ca++
- In addition to the ubiquitously expressed m- and m- calpains, some tissue-specific calpains have been identified
- The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.