NGF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-399-Each-of-1 | In Stock | ₹ 41,563.00 |
01-674-399 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,563.00
GST (18%): ₹ 7,481.34
Total Price: ₹ 49,044.34
Antigen
NGF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NGF
Gene Alias
B nerve growth factor; beta ngf; beta-nerve growth factor; BetaNGF; beta-NGF; bNGF; b-NGF; HSAN5; MGC161426; MGC161428; nerve growth factor; nerve growth factor (beta polypeptide); nerve growth factor, beta; nerve growth factor, beta polypeptide; nerve growth factor, beta subunit; NGF; NGF b; NGF β; Ngfb; NGFbeta; NGFβ; β nerve growth factor; β NGF; βNGF
Host Species
Chicken
Purification Method
IgY fraction
Regulatory Status
RUO
Gene ID (Entrez)
18049, 310738, 4803
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P01138, P01139, P25427
Gene Symbols
NGF
Immunogen
Synthetic peptides corresponding to residues 74-85 & 113-124 of mouse NGF protein.
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgY
Related Products
Description
- PA1-9516 detects Nerve growth factor in human, mouse and rat samples
- PA1-9516 has been successfully used in Western blot, Immunohistochemistry and ELISA procedures
- The PA1-9516 immunogen is a synthetic peptides corresponding to residues 74-85 & 113-124 of mouse NGF protein
- Nerve growth factor (NGF) influences the survival and differentiation of a variety of neuronal and nonneuronal cells
- The actions of this polypeptide result from binding to specific cell surface receptors which are present as both high and low affinity sites
- Although both types of receptor bind NGF only the high affinity form is capable of signal transduction
- Cross-linking studies with 125I-NGF have shown that the high affinity receptor of rat PC12 cells forms an Mr 158,000 complex with NGF while the low affinity receptor forms an Mr 100,000 complex
- Full length cDNA clones for both the human and rat NGF receptor genes have been produced and sequenced, revealing greater than 90% homology between the two species
- NGF exhibits nerve growth stimulating activity and is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons
- Further, NGF stimulates division and differentiation of sympathetic and embryonic sensory neurons
- Mutations in the NGF gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of NGF gene expression is associated with allergic rhinitis.