alpha-1 Antitrypsin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-412-Each-of-1 | In Stock | ₹ 32,040.00 |
01-674-412 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,040.00
GST (18%): ₹ 5,767.20
Total Price: ₹ 37,807.20
Antigen
alpha-1 Antitrypsin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SERPINA1
Gene Alias
a-1 AT; A1A; a1-antitrypsin; A1AT; AAT; Aat2; Aat-2; alpha 1 antitrypsin; alpha-1 antitrypsin; alpha-1 protease inhibitor; Alpha-1 protease inhibitor 1; alpha-1-antiproteinase; Alpha-1-antitrypsin; alpha-1-antitrypsin (protease inhibitor); alpha-1-antitrypsin 1-1; alpha-1-antitrypsin 2; alpha-1-antitrypsin null; alpha1AT; alpha-1-protease inhibitor; alpha-1-proteinase inhibitor; Digestive Zymogen; Dom1; MGC23330; MGC9222; PI; PI1; PRO0684; PRO2209; PRO2275; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1); Protease Serine 1; serine (or cysteine) peptidase inhibitor, clade A, member 1A; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1a; Serine Protease 1; serine protease inhibitor 1-1; Serine protease inhibitor A1a; serine protease inhibitor alpha 1; serine proteinase inhibitor, clade A, member 1; serpin A1; Serpin A1a; serpin family A member 1; serpin peptidase inhibitor clade A member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; SERPINA1; Serpina1a; Short peptide from AAT; SPAAT; Spi1; Spi1-1; Spi1-3; TRP1; TRY1
Host Species
Chicken
Purification Method
IgY fraction
Regulatory Status
RUO
Gene ID (Entrez)
5265
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P01009
Gene Symbols
SERPINA1
Immunogen
Synthetic peptide based on the human alpha-1 antitrypsin protein.
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgY
Related Products
Description
- PA1-9529 detects Alpha1 trypsin in human samples
- PA1-9529 has been successfully used in Western blot and ELISA procedures
- By Western blot, PA1-9529 detects a 46 kDa protein representing Alpha1 trypsin
- PA1-9529 immunogen is a synthetic peptide based on the human alpha-1 antitrypsin protein
- Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung
- In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma
- Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn
- Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation
- Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.