01-674-425

DNMT3B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-674-425-Each-of-1 In Stock ₹ 28,613.50

01-674-425 - Each of 1

₹ 28,613.50

In Stock

Quantity

1

Base Price: ₹ 28,613.50

GST (18%): ₹ 5,150.43

Total Price: ₹ 33,763.93

Antigen

DNMT3B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Dnmt3b

Gene Alias

DNA (cytosine-5-)-methyltransferase 3 beta; DNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase 3 beta; DNA methyltransferase 3B; DNA methyltransferase HsaIIIB; DNA methyltransferase MmuIIIB; DNA MTase HsaIIIB; DNA MTase MmuIIIB; Dnmt3; DNMT3B; ICF; ICF1; M.HsaIIIB; m.MmuIIIB; MGC1090; MmuIIIB

Host Species

Chicken

Purification Method

IgY fraction

Regulatory Status

RUO

Gene ID (Entrez)

1789

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q9UBC3

Gene Symbols

Dnmt3b

Immunogen

Purified recombinant DNMT3L.1 corresponding to the chromosome 21 gene (Human).

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgY

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Description

  • PA1-9542 detects DNMT3L in human samples
  • PA1-9542 has been successfully used in Western blot procedures
  • By Western blot, PA1-9542 detects a 47 kDa protein representing DNMT3L
  • PA1-9542 immunogen is a purified recombinant DNMT3L.1 corresponding to the chromosome 21 gene (Human)
  • CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation
  • Studies in mice have demonstrated that DNA methylation is required for mammalian development
  • This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation
  • The protein localizes primarily to the nucleus and its expression is developmentally regulated
  • Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome
  • Six alternatively spliced transcript variants have been described
  • The full length sequences of variants 4 and 5 have not been determined.