LXR alpha/beta Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-650-Each-of-1 | In Stock | ₹ 46,591.50 |
01-674-650 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
LXR alpha/beta
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NR1H2
Gene Alias
AI194859; AU018371; liver X nuclear receptor alpha variant 1; liver X nuclear receptor beta; Liver X Receptor; liver X receptor alpha; Liver X receptor beta; LX receptor beta; LXR; LXR alpha; LXR beta; LXRA; LXR-a; LXRalpha; LXRB; LXR-b; LXRbeta; NER; NER1; NER-I; NR1H2; NR1H3; nuclear orphan receptor LXR-alpha; nuclear orphan receptor LXR-beta; nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 2; nuclear receptor subfamily 1, group H, member 3; OR-1; Orphan nuclear receptor OR-1; oxysterols receptor LXR-alpha; Oxysterols receptor LXR-beta; retinoid X receptor-interacting protein No.15; Rip15; RLD1; RLD-1; steroid hormone-nuclear receptor NER; ubiquitous receptor; ubiquitously-expressed nuclear receptor; ubiquitously-expressed nuclear receptor 1; ubiquitously-expressed nuclear receptor 2; Unr; Unr1; Unr2; UR
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
10062, 7376
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
P55055, Q13133
Gene Symbols
NR1H2, NR1H3
Immunogen
Internal sequence corresponding to amino acids CRLQDKKLPPLLSEI.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with bovine and canine based on sequence homology
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000
- NR1H3 (oxysterols receptor LXR-alpha) is a nuclear receptor that exhibits a ligand-dependent transcriptional activiation activity
- Its interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES
- LXRES are DR4-type response elements characterized by direct repeats of two similar hexanucleotide half-sites spaced by four nucleotides
- NR1H3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiqutination of LDLR, VLDLR, and LRP8
- It also interplays functionally with RORA for the regulation of genes involves in liver metabolism.