TIMP3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-674-740-Each-of-1 | In Stock | ₹ 72,223.50 |
01-674-740 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 72,223.50
GST (18%): ₹ 13,000.23
Total Price: ₹ 85,223.73
Antigen
TIMP3
Classification
Polyclonal
Formulation
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.
P35625
Gene Symbols
TIMP3
Immunogen
Synthetic peptide derived from the C-terminus of human TIMP-3
Quantity
1 mL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin)
Conjugate
Unconjugated
Gene
TIMP3
Gene Alias
HSMRK222; K222; K222TA2; Metalloproteinase inhibitor 3; MIG-5 protein; protein MIG-5; SFD; Sun; TIMP 3; TIMP metallopeptidase inhibitor 3; TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory); TIMP metallopeptidase inhibitor 3 L homeolog; timp3; TIMP-3; TIMP-3 protein; timp3.L; timp3-A; tissue inhibitor metalloproteinase-3; tissue inhibitor of metalloproteinase 3; tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory); tissue inhibitor of metalloproteinase-3; tissue inhibitor of metalloproteinase-3 precursor; tissue inhibitor of metalloproteinases 3; tissue inhibitor of metalloproteinases-3; XELAEV_18002484mg
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7078
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody is predicted to react with rabbit and baboon based on sequence homology
- Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
- Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature
- A suggested positive control is placenta or breast carcinoma
- Tissue inhibitor of metalloproteinase 3 (TIMP3) is a member of the tissue inhibitor of metalloproteinases gene family
- It functions to inhibit the activity of matrix metalloproteinases (MMP) which degrade components of the extracellular matrix
- TIMP3 is expressed upon mitogenic stimulation
- It binds irreversibly to zinc-dependent MMPs and inactivates them by binding to their catalytic zinc cofactor
- Other functions of TIMP3 include nervous system development, tissue regeneration, and visual perception
- In humans, the gene encoding TIMP3 is located on chromosome 22.