01-674-825

Calcium Channel beta-4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-674-825-Each-of-1 In Stock ₹ 46,502.50

01-674-825 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Calcium Channel beta-4

Classification

Polyclonal

Formulation

PBS with 0.08% sodium azide

Gene Accession No.

O00305

Gene Symbols

Cacnb4

Immunogen

Synthetic peptide, conjugated to KLH, corresponding to the rat calcium channel beta4 subunit.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

Cacnb4

Gene Alias

3110038O15Rik; CAB4; Cacnb4; CACNLB4; calcium channel beta 4 subunit; calcium channel voltage-dependent subunit beta 4; calcium channel, voltage-dependent, beta 4 subunit; calcium voltage-gated channel auxiliary subunit beta 4; Cchb4; dihydropyridine-sensitive L-type, calcium channel beta-4 subunit; EA5; EIG9; EJM; EJM4; EJM6; lh; OTTHUMP00000207247; OTTHUMP00000207249; Voltage-dependent L-type calcium channel subunit beta-4

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

785

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • A suggested positive control for this product is rat brain lysate
  • This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins
  • Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio
  • Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing
  • The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation
  • Certain mutations in this gene have been associated with idiopathic generalized epilepsy and juvenile myoclonic epilepsy
  • Multiple transcript variants encoding different isoforms have been found for this gene.