01-674-839

TYROBP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-674-839-Each-of-1 In Stock ₹ 49,439.50

01-674-839 - Each of 1

₹ 49,439.50

In Stock

Quantity

1

Base Price: ₹ 49,439.50

GST (18%): ₹ 8,899.11

Total Price: ₹ 58,338.61

Antigen

TYROBP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TYROBP

Gene Alias

DAP12; DNAX-activation protein 12; KARAP; KAR-associated protein; killer cell activating receptor associated protein; killer cell activating receptor-associated protein; killer-activating receptor-associated protein; Ly83; PLOSL; TYRO protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein; Tyrobp

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

22177, 7305

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.08% sodium azide

Gene Accession No.

O43914, O54885

Gene Symbols

TYROBP

Immunogen

Recombinant DAP12 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control for this product is NKp44 positive cells
  • DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells
  • DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction
  • Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.