01-675-202

MRE11 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-675-202-Each-of-1 In Stock ₹ 46,502.50

01-675-202 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MRE11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mre11

Gene Alias

ATLD; AT-like disease; DNA recombination and repair protein; double-strand break repair protein MRE11; Double-strand break repair protein MRE11A; endo/exonuclease Mre11; HNGS1; Meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A; meiotic recombination 11 homolog A (S. cerevisiae); mmMRE11A; MRE11; MRE11 double strand break repair nuclease A; MRE11 homolog 1; MRE11 homolog A; MRE11 homolog A, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease A; MRE11 meiotic recombination 11 homolog A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); MRE11 meiotic recombination 11-like protein A; MRE11A; MRE11B; MRX complex nuclease subunit; NGS1; RAD58; XRS4; YM9959.06C; YMR224C

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

4361

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P49959

Gene Symbols

Mre11

Immunogen

Synthetic peptide corresponding to a portion of human MRE11.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Suggested positive control: 293 whole cell lysate
  • MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex
  • This complex plays a central role in double-strand break repair, DNA recombination, maintenance of telomere integrity and meiosis
  • The complex possesses single-stranded endonuclease activity and double-strand-specific 3'-5' exonuclease activity which are provided by MRE11
  • RAD50 is required to bind DNA ends and hold them in close proximity
  • Mutations in the gene could result in ataxia-telangiectasia-like disorder 1.