01-675-216

Importin 8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-675-216-Each-of-1 In Stock ₹ 46,502.50

01-675-216 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Importin 8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IPO8

Gene Alias

6230418K12Rik; Abcc10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; C130009K11Rik; FLJ26580; imp8; importin 8; importin-8; IPO8; MRP7; Om1; OM-1; oocyte maturation 1; RAN binding protein 8; ran-binding protein 8; RANBP8

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

10526

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O15397

Gene Symbols

IPO8

Immunogen

Synthetic peptide corresponding to residues 850-900 of human Importin-8.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • Importin 8 is a 1037 amino acid nuclear protein with a RAN binding site
  • It belongs to RAN-binding protein super family and hence shares an N-terminal sequence motif with importin-beta that appears to account for RAN GTP binding
  • It binds to the nuclear pore complex (NPC) and is well known as a transport carrier that mediates nuclear import of ribosomal proteins with a classical nuclear localization signal
  • Importin 8 works by binding to the nuclear pore complex and, along with RANGTP and RANBP1, inhibits the GAP stimulation of the RAN GTPase
  • Along with transportin it also helps in the nuclear import of SRP19.