01-675-626

TRAF7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-675-626-Each-of-1 In Stock ₹ 46,502.50

01-675-626 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TRAF7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TRAF7

Gene Alias

DKFZp586I021; E3 ubiquitin-protein ligase TRAF7; MGC7807; RFWD1; RGD1559653; ring finger and WD repeat domain 1; ring finger and WD repeat domain 1 isoform 1; RING finger and WD repeat-containing protein 1; RING finger protein 119; RING-type E3 ubiquitin transferase TRAF7; RNF119; TNF receptor associated factor 7; TNF receptor-associated factor 7; TNF receptor-associated factor 7, E3 ubiquitin protein ligase; traf7

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100065698, 224619, 360491, 84231

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

1.0 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q6Q0C0, Q922B6

Gene Symbols

TRAF7

Immunogen

Synthetic peptide corresponding to residues 334-356 of human TRAF7.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Equine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Suggested positive control: antigen standard for TRAF7 (transient overexpression lysate)
  • TRAFs are signal transducers for members of TNFR superfamily
  • These are critically involved in activation of MAP3K family members involved in NF-kappaB and JNK activation and apoptosis
  • TRAF7, a novel 670 A
  • A protein, is a human homolog of mouse Traf7 andconsists of an N-terminal RING finger domain, central TRAF domain, a coiled-coil motif and 7 WD40 repeats at the C-terminus
  • It has E3-ubiquitin ligase activity for self-ubiquitination
  • TRAF7 specifically interacts with MEKK3 and mediates MEKK3-induced AP1 and CHOP activation and induces apoptosis through Caspase-independent pathways
  • It is a multifunctional protein involved in sumoylation and negative regulation of c-Myb, thereby regulating proliferation and differentiation of hematopoietic cells.