GAPDHS Monoclonal Antibody (Hs-8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-675-999-Each-of-1 | In Stock | ₹ 41,385.00 |
01-675-999 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
GAPDHS
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 15mM sodium azide; pH 8
Gene Accession No.
O14556
Gene Symbols
GAPDHS
Immunogen
Freshly ejaculated human sperms.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Porcine
Product Type
Antibody
Isotype
IgM
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Clone
Hs-8
Conjugate
Unconjugated
Gene
GAPDHS
Gene Alias
epididymis secretory protein Li 278; GAPD2; GAPDH S; GAPDH2; gapdh-2; GAPDHS; GAPDS; Gapd-s; glyceraldehyde-3-phosphate dehydrogenase type 2; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; glyceraldehyde-3-phosphate dehydrogenase, testis-specific; HEL-S-278; HSD35; HSD-35; LOW QUALITY PROTEIN: glyceraldehyde-3-phosphate dehydrogenase, testis-specific; spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase
Host Species
Mouse
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100517097, 26330
Content And Storage
4° C, do not freeze
Form
Liquid
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Description
- For ICC staining, membrane permeabilization with acetone is essential
- Purity is >95% by SDS-PAGE
- Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) is a metabolic enzyme responsible for catalyzing one step in the glycolytic pathway, the reversible oxidative phosphorylation of glyceraldehyde 3-phosphate
- Because GAPDH is a protein expressed in large amounts and which is required at all times for important "ehouse keeping"e functions, levels of GAPDH mRNA are often measured and used as standards in studies of mRNA expression
- Increasingly, scientists are making use of specific antibodies to GAPDH in comparable studies of levels of protein expression
- GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer's disease, and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington's disease
- Associations with actin and tubulin have also been reported
- The protein may also have a role in the regulation of apoptosis, and interestingly migrates from the cytoplasm into the nucleus when cells become apoptotic.