01-676-002
Epstein Barr Virus Nuclear Antigen 1 Monoclonal Antibody (E1-2.5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-002-Each-of-1 | In Stock | ₹ 29,325.50 |
01-676-002 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 29,325.50
GST (18%): ₹ 5,278.59
Total Price: ₹ 34,604.09
Antigen
Epstein Barr Virus Nuclear Antigen 1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG2b
Applications
ELISA, Immunocytochemistry
Clone
E1-2.5
Conjugate
Unconjugated
Gene Alias
EBNA-1
Immunogen
Epstein-Baar nuclear antigen 1.
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
4° C, do not freeze
Form
Liquid
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Description
- This antibody recognizes the repetitive Gly-Ala region of the Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA-1)
- Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents
- EBV latently infects B lymphocytes
- Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B
- LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases
- Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.