STAT1 Monoclonal Antibody (SM2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-127-Each-of-1 | In Stock | ₹ 48,015.50 |
01-676-127 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,015.50
GST (18%): ₹ 8,642.79
Total Price: ₹ 56,658.29
Antigen
STAT1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P42224
Gene Symbols
STAT1
Immunogen
STAT1 peptide sequence 8-23 (QLDSKFLEQVHQLYD), conjugated to KLH.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunoprecipitation, Western Blot
Clone
SM2
Conjugate
Unconjugated
Gene
STAT1
Gene Alias
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
6772
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- This antibody recognizes an epitope included within amino acids 8-23 of STAT1
- Western Blot: Reducing conditions
- STAT1 (signal transducers and activators of transcription 1) is a member of the STAT family of transcription factors
- STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6
- STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism
- Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure
- The STAT1 gene is located on chromosome 2
- STAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors
- After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus to regulate transcription of many different genes
- Among the seven STATs types, STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile
- STAT1 is activated by many different ligands including IFN family (IFN-Alpha, IFN-Beta, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1)
- Two alternatively spliced transcript variants encoding distinct isoforms of STAT1 have been described.