01-676-133

CD41 Monoclonal Antibody (HIP2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-676-133-Each-of-1 In Stock ₹ 38,982.00

01-676-133 - Each of 1

₹ 38,982.00

In Stock

Quantity

1

Base Price: ₹ 38,982.00

GST (18%): ₹ 7,016.76

Total Price: ₹ 45,998.76

Antigen

CD41

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 15mM sodium azide; pH 8.0

Gene Accession No.

P08514

Gene Symbols

Itga2b

Immunogen

Human CD41b.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG3

Applications

Flow Cytometry, Immunohistochemistry (Frozen)

Clone

HIP2

Conjugate

Unconjugated

Gene

Itga2b

Gene Alias

AI172977; alpha IIb; alphaIIb; alphaIIb protein; BDPLT16; BDPLT2; CD41; CD41B; form 1; form 2; GP IIb; GP2B; GPalpha IIb; GPIIb; GT; GTA; HPA3; integrin alpha 2b; integrin alpha 2b (Cd41b); integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; integrin subunit alpha 2b; integrin subunit alpha IIb; integrin, alpha 2B; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb; platelet glycoprotein IIb of IIb/II Ia complex; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3674

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • This antibody reacts with beta (b) subunit of CD41 glycoprotein (light chain; 23 kDa)
  • CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor
  • CD41 is also involved in blood coagulation by mediating platelet aggregation
  • Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin
  • CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation
  • Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.