CD45RO Monoclonal Antibody (UCHL1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-187-Each-of-1 | In Stock | ₹ 43,743.50 |
01-676-187 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,743.50
GST (18%): ₹ 7,873.83
Total Price: ₹ 51,617.33
Antigen
CD45RO
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P08575
Gene Symbols
PTPRC
Immunogen
Human IL-2 dependent T cells.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone
UCHL1
Conjugate
Unconjugated
Gene
PTPRC
Gene Alias
B220; Cd45; CD45 antigen; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5788
Content And Storage
4° C, do not freeze
Form
Liquid
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Description
- Pretreatment note: MA1-19452 does not require protein digestion pretreatment of paraffin sections and does not require antigen retrieval using heat treatment prior to staining of paraffin sections
- A suggested positive control for this product is tonsil tissue
- CD45RO (UCHL1, ubiquitin carboxyl terminal esterase L1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein
- CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
- CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains
- CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
- CD45RO is expressed on macrophages, CD8+ T cells, activated T cells and myeloma cells
- Besides the role in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.