IRAK4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 01-676-652-Each-of-1 | In Stock | ₹ 46,146.50 |
01-676-652 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,146.50
GST (18%): ₹ 8,306.37
Total Price: ₹ 54,452.87
Antigen
IRAK4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRAK4
Gene Alias
8430405M07Rik; 9330209D03Rik; interleukin 1 receptor associated kinase 4; interleukin-1; interleukin-1 receptor-associated kinase 4; IPD1; Irak4; IRAK-4; NY-REN-64; REN64; renal carcinoma antigen NY-REN-64
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
266632, 300177, 51135
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q8R4K2, Q9NWZ3
Gene Symbols
IRAK4
Immunogen
Synthetic peptides corresponding to residues 38-54 and 120-136 of mouse IRaK-4.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Suggested positive control: antigen standard for IRAK4 (transient overexpression lysate), NIH-3T3 whole cell lysate
- IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways
- Overexpression of IRAK-4 activates NF-kappa-B and MAPK pathways
- IRAK-4 interacts with and phosphorylates IRAK-1
- IRAK-4-deficient animals are completely resistant to the challenge with LPS
- Animals and humans lacking IRAK-4 are impaired in their responses to viral and bacterial challenges
- Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses and in innate immunity.