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01-950-108

Phospho-AKT1 (Ser473) Monoclonal Antibody (104A282), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01-950-108-Each-of-1 In Stock ₹ 53,667.00

01-950-108 - Each of 1

₹ 53,667.00

In Stock

Quantity

1

Base Price: ₹ 53,667.00

GST (18%): ₹ 9,660.06

Total Price: ₹ 63,327.06

Antigen

Phospho-AKT1 (Ser473)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P31749, P31750

Gene Symbols

AKT1

Immunogen

This monoclonal antibody was raised against a synthetic peptide containing phosphorylated serines at amino acid residues 473 of human Akt1.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Chicken, Human, Mouse, Zebrafish

Product Type

Antibody

Isotype

IgG1

Applications

ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

104A282

Conjugate

Unconjugated

Gene

AKT1

Gene Alias

Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase; serine-threonine protein kinase; Thymoma viral proto-oncogene; thymoma viral proto-oncogene 1; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene-like protein 1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

101910198, 11651, 207, 395928

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Description

  • MA1-20325 detects phospho-AKT1 (pS473) in human and mouse samples
  • AKT1 (PKB alpha) is a serine/threonine kinase that regulates cell survival
  • The activated enzyme inhibits apoptosis and stimulates cell cycle progression by phosphorylating numerous targets in various cell types, including cancer cells
  • This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors
  • Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9
  • The AKT pathway is a major target for cancer drug discovery.