01672456

C5AR1 Monoclonal Antibody (P12/1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 01672456-Each-of-1 In Stock ₹ 72,980.00

01672456 - Each of 1

₹ 72,980.00

In Stock

Quantity

1

Base Price: ₹ 72,980.00

GST (18%): ₹ 13,136.40

Total Price: ₹ 86,116.40

Antigen

C5AR1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P21730

Gene Symbols

C5AR1

Immunogen

C5aR - peptide: Met1 - Asn31.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Western Blot

Clone

P12/1

Conjugate

Unconjugated

Gene

C5AR1

Gene Alias

anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

728

Content And Storage

4° C

Form

Liquid

Description

  • CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known
  • C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract
  • CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a
  • Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production
  • CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex
  • Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.