CD337 (NKp30) Monoclonal Antibody (AF29-4D12), PE, eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 12-337-941-Each | In Stock | ₹ 11,449.85 |
12-337-941 - Each
In Stock
Quantity
1
Base Price: ₹ 11,449.85
GST (18%): ₹ 2,060.973
Total Price: ₹ 13,510.823
Antigen
CD337 (NKp30)
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
O14931, Q8MJ02
Gene Symbols
Ncr3
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
259197, 715574
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
AF29-4D12
Conjugate
PE
Gene
Ncr3
Gene Alias
1C7; Activating natural killer receptor p30; activating NK-A1 receptor; CD337; LY117; lymphocyte antigen 117; MALS; Natural cytotoxicity triggering receptor 3; natural killer cell p30-related protein; natural killer cell receptor; Ncr3; NK receptor 1c7; Nkp30; NK-p30; NKp30S; NKp30v1; NKp30v1ED
Host Species
Mouse
Quantity
25 Tests
Primary or Secondary
Primary
Target Species
Human, Non-human Primate, Rhesus Monkey
Product Type
Antibody
Isotype
IgG1 κ
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Description
- Description: This AF29-4D12 monoclonal antibody reacts with human CD337, which is also known as NKp30
- Expressed on NK cells, CD337 is the predominant member of the natural cytotoxicity receptor family that also includes NKp46 and NKp44
- CD337 is involved in activating and expanding resting NK cells following interaction with dendritic cells to eliminate tumor, virus-infected, and immature dendritic cells
- Several ligands for this receptor have been reported, including B7-H6
- The AF29-4D12 antibody has been reported to crossreact to rhesus macaque
- Applications Reported: This AF29-4D12 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This AF29-4D12 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
- This can be used at 5 μL (0.125 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
- Filtration: 0.2 μm post-manufacturing filtered
- The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells
- The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor
- A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility
- Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010].