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12-987-542

CD367 (Clec4A, DCIR) Monoclonal Antibody (9E8), PE, eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 12-987-542-Each-of-1 In Stock ₹ 35,422.00

12-987-542 - Each of 1

₹ 35,422.00

In Stock

Quantity

1

Base Price: ₹ 35,422.00

GST (18%): ₹ 6,375.96

Total Price: ₹ 41,797.96

Antigen

CD367 (Clec4A, DCIR)

Classification

Monoclonal

Concentration

5 μL/Test

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q9UMR7

Gene Symbols

CLEC4A

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

50856

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry

Clone

9E8

Conjugate

PE

Gene

CLEC4A

Gene Alias

CD367; CLEC4A; Clec4a2; Clecsf6; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6; C-type lectin DDB27; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; C-type lectin domain family 4, member a2; C-type lectin superfamily member 6; DCIR; Dcir1; Dcir2; DDB27; Dendritic cell immunoreceptor; dendritic cell inhibitory receptor 1; dendritic cell inhibitory receptor 2; HDCGC13P; immunoreceptor; lectin-like immunoreceptor; LLIR

Host Species

Mouse

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Description

  • Description: This 9E8 monoclonal antibody reacts with human CD367, also known as dendritic cell immunoreceptor (DCIR) or Clec4A
  • This C-type lectin is expressed on monocytes, granulocytes, B cells, and plasmacytoid dendritic cells in peripheral blood
  • DCIR is also expressed on mature and immature monocyte-derived dendritic cells in vitro
  • DCIR is not expressed on NK or T cells
  • With its cytoplasmic ITIM domain, DCIR is an inhibitory receptor that recruits the SHP-1 and SHP-2 phosphatases upon ligand binding
  • Studies have demonstrated that DCIR plays a role in the interaction between dendritic cells and HIV-1
  • Applications Reported: This 9E8 antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This 9E8 antibody has been pre-titrated and tested by flow cytometric analysis of human peripheral blood cells
  • This can be used at 5 μL (0.25 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily
  • Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response
  • The encoded type 2 transmembrane protein may play a role in inflammatory and immune response
  • Multiple transcript variants encoding distinct isoforms have been identified for this gene
  • This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.