14-166-137

CD166 (ALCAM) Monoclonal Antibody (eBioALC48), eBioscience™, Invitrogen™

Manufacturer: Invitrogen

Select a Size

Pack Size SKU Availability Price
Each of 1 14-166-137-Each-of-1 In Stock ₹ 1,23,532.00

14-166-137 - Each of 1

₹ 1,23,532.00

In Stock

Quantity

1

Base Price: ₹ 1,23,532.00

GST (18%): ₹ 22,235.76

Total Price: ₹ 1,45,767.76

Antigen

CD166 (ALCAM)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

Q61490

Gene Symbols

ALCAM

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11658

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin)

Clone

eBioALC48

Conjugate

Unconjugated

Gene

ALCAM

Gene Alias

activated leukocyte cell adhesion molecule; AI853494; ALCAM; BEN; CD166; CD166 antigen; cell adhesion molecule; DM-GRASP; FLJ38514; HB2; KG-CAM; MEMD; MGC71733; MuSC; Protein DM-GRASP; Protein MEMD; SB-10 antigen; SC1; unnamed protein product

Host Species

Rat

Quantity

2 mg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Activated leukocyte cell adhesion molecule (ALCAM; CD166) is a 105 kD cell-surface adhesion molecule belonging to the Ig superfamily of receptors
  • ALCAM is a type I transmembrane glycoprotein, possessing five extracellular Ig domains, a transmembrane domain, and a short cytoplasmic tail
  • ALCAM is involved in homotypic adhesion, as well as heterotypic adhesion with its natural ligand, CD6
  • A soluble isoform of ALCAM has been shown to inhibit homophilic adhesive interactions
  • ALCAM is expressed on a variety of cell types, including activated T and B cells, monocyte-derived dendritic cells, and thymic epithelial cells
  • ALCAM expression has also been used as a marker for the isolation of pluripotent stem cells
  • This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain
  • This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration
  • Multiple alternatively spliced transcript variants encoding different isoforms have been found.