14-589-137
CD249 (BP-1) Monoclonal Antibody (6C3), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-589-137-Each-of-1 | In Stock | ₹ 1,22,108.00 |
14-589-137 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,22,108.00
GST (18%): ₹ 21,979.44
Total Price: ₹ 1,44,087.44
Antigen
CD249 (BP-1)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P16406
Gene Symbols
Enpep
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13809
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Clone
6C3
Conjugate
Unconjugated
Gene
Enpep
Gene Alias
6030431M22Rik; Aminopeptidase A; aminopeptidase-A; APA; AP-A; BP1; Bp-1/6C3; BP-1/6C3 antigen; CD249; differentiation antigen gp160; EAP; ENPEP; Glutamyl aminopeptidase; glutamyl aminopeptidase (aminopeptidase A); gp160; Ly51; Ly-51
Host Species
Rat
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The 6C3 monoclonal antibody reacts with mouse BP-1, also known as Ly-51 and 6C3 antigen
- BP-1 is a 140 kDa type II transmembrane protein that is present on the surface as a disulfide-linked homodimer
- This molecule is an enzyme with aminopeptidase A (APA) activity and is expressed by bone marrow stromal cells, thymic cortical epithelial cells and at early stages of mouse B cell development, on pre-B cells
- The low level of BP-1 expression on pre-B cells can be upregulated in the presence of IL-7
- Applications Reported: The 6C3 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, and immunohistochemical staining
- Applications Tested: The 6C3 antibody has been tested by flow cytometric analysis of mouse bone marrow cells
- This can be used at less than or equal to 1 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- CD249 appears to have a role in the catabolic pathway of the renin-angiotensin system
- Probably plays a role in regulating growth and differentiation of early B-lineage cells.