IL-4 Monoclonal Antibody (BVD6-24G2), eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | 14-704-285-Each | In Stock | ₹ 21,951.85 |
14-704-285 - Each
In Stock
Quantity
1
Base Price: ₹ 21,951.85
GST (18%): ₹ 3,951.333
Total Price: ₹ 25,903.183
Antigen
IL-4
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P07750
Gene Symbols
Il4
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16189
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry
Clone
BVD6-24G2
Conjugate
Unconjugated
Gene
Il4
Gene Alias
B cell growth factor 1; B_cell stimulatory factor 1; B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; cytokine; H-IL-4; IGG1 induction factor; IL2; IL4; Il-4; Il4e12; ILN; Interleukin; interleukin 4; interleukin 4 variant 2; interleukin 4 variant IL-4delta2; interleukin 4 variant IL-4delta3; interleukin 4 variant IL-4int2A; interleukin 4 variant IL-4int3A; interleukin 4 variant IL-4int3B; Interleukin4; interleukin-4; interleukin-4 precursor; lymphocyte stimulatory factor 1; MGC79402; M-IL-4; Pitrakinra
Host Species
Rat
Quantity
500 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG1 κ
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Description
- Description: The BVD6-24G2 antibody reacts with mouse interleukin-4 (IL-4), a 14 kDa cytokine secreted by Th2 cells
- Applications Reported: BVD6-24G2 is used for detection of mouse IL-4 by ELISA
- Applications Tested: The BVD6-24G2 antibody has been tested by sandwich ELISA for detection of mouse IL-4 in combination with 11B11 and can be used between 0.5-2 μg/mL
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor
- IL-4 has been found to have the broadest range of actions
- The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13
- STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4
- The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q
- In particular, IL-4 is located in close proximity to IL13 on the chromosome
- Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome
- IL-4 delta 2 is a known splice variant of IL-4.