CD271 (NGF Receptor) Monoclonal Antibody (ME20.4), eBioscience™, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 14-940-037-Each-of-1 | In Stock | ₹ 1,22,108.00 |
14-940-037 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,22,108.00
GST (18%): ₹ 21,979.44
Total Price: ₹ 1,44,087.44
Antigen
CD271 (NGF Receptor)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.2
Gene Accession No.
P07174, P08138, Q9Z0W1
Gene Symbols
Ngfr
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100349095, 100525607, 101119064, 18053, 24596, 4804, 491071
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
ME20.4
Conjugate
Unconjugated
Gene
Ngfr
Gene Alias
CD271; CD271 antigen; Gp80-LNGFR; LNGFR; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 16; low-affinity nerve growth factor receptor; nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; NGFR; NGR; p75; p-75; p75 ICD; p75 neurotrophin receptor; p75 ntr; p75(NTR); p75NGFR; p75NTR; RNNGFRR; TNFR superfamily, member 16; Tnfrsf16; TNR16; Tumor necrosis factor receptor superfamily member 16
Host Species
Mouse
Quantity
2 mg
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse, Non-human Primate, Ovine, Porcine, Rabbit, Rat
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- The MAb ME20.4 recognizes CD271, a 75 kDa type I transmembrane protein that belongs to the low-affinity neurotrophin receptor and tumor necrosis factor receptor superfamily
- CD271 is expressed by neurons, Schwann cells, melanocytes, mesenchymal stem/stromal cells, neural crest stem cells, astrocytes, oligodendrocytes, and a subset of lymphoid cells including follicular dendritic cells
- CD271 binds to the ligands NGF, BDNF, NTF3, and NTF4
- CD271 contains a death domain which induces apoptosis and regulates cell growth and proliferation through interactions with TRAF2, TRAF4, TRAF6, PTPN13, and RANBP9
- The ME20.4 MAb recognizes human, Non-human Primate, mouse, rat, sheep, rabbit, cat, dog, and pig CD271
- Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types
- Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo
- Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.