14-977-395

SOX11 Monoclonal Antibody (SOX11-C1), eBioscience™, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 14-977-395-Each-of-1 In Stock ₹ 3,06,605.00

14-977-395 - Each of 1

₹ 3,06,605.00

In Stock

Quantity

1

Base Price: ₹ 3,06,605.00

GST (18%): ₹ 55,188.90

Total Price: ₹ 3,61,793.90

Antigen

SOX11

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.

P35716

Gene Symbols

SOX11

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6664

Content And Storage

4° C

Form

Liquid

Applications

ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

SOX11-C1

Conjugate

Unconjugated

Gene

SOX11

Gene Alias

1110038H03Rik; 6230403H02Rik; AI836553; end1; MRD27; Sox11; Sox-11; SRY; SRY (sex determining region Y)-box 11; SRY (sex-determining region Y)-box 11; SRY-box 11; SRY-box containing gene 11; SRY-box transcription factor 11; SRY-related HMG-box gene 11; transcription factor SOX-11

Host Species

Mouse

Quantity

10 mg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

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Description

  • Description The MAb SOX11-C1 (C1) recognizes human Sox11
  • The transcription factor Sox11 is a member of the SOX (sex determining region Y-related HMG (High Mobility Group) Box) family of proteins
  • Under normal conditions Sox11 is expressed in the developing central nervous system during embryogenesis and has sequence homology to Sox4
  • Sox11 plays a role in neuronal maturation and epithelial-mesenchymal interactions and is required for the survival of neuronal and mesenchymal progenitor cells
  • Sox11 is expressed in mantle cell lymphoma (MCL) and in subsets of hairy cell leukemias, Burkitt lymphomas, and B cell lymphoblastic leukemias, but is not expressed in other B cell lymphomas or in normal B lymphocytes
  • Sox11 is also expressed in epithelial ovarian cancer and gliomas
  • This intronless gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate
  • The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins
  • The protein may function in the developing nervous system and play a role in tumorigenesis.