CD4 Monoclonal Antibody (RPA-T4), PE-Cyanine5, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 15-004-941-Each-of-1 | In Stock | ₹ 11,481.00 |
15-004-941 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 11,481.00
GST (18%): ₹ 2,066.58
Total Price: ₹ 13,547.58
Antigen
CD4
Classification
Monoclonal
Concentration
5 μL/Test
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Accession No.
P01730
Gene Symbols
CD4
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
920
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Liquid
Applications
Flow Cytometry
Clone
RPA-T4
Conjugate
PE-Cyanine5
Gene
CD4
Gene Alias
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen
Host Species
Mouse
Quantity
25 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- The RPA-T4 MAb reacts with human CD4, a 59 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells (T-helper cells) and in low levels on monocytes
- CD4 is a receptor for the human immunodeficiency virus (HIV)
- RPA-T4 blocks HIV binding and mixed lymphocyte reaction
- The RPA-T4 antibody recognizes a different epitope than the OKT4 MAb, and these antibodies do not cross-block binding to each other's respective epitopes
- The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV
- CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells
- At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues
- CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck
- It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system
- Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].