CD4 Monoclonal Antibody (GK1.5), Functional Grade, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 16-004-1050-Each-of-1 | In Stock | ₹ 12,85,160.00 |
16-004-1050 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,85,160.00
GST (18%): ₹ 2,31,328.80
Total Price: ₹ 15,16,488.80
Antigen
CD4
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.2
Gene Accession No.
P06332
Gene Symbols
CD4
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12504
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Functional Assay, Neutralization
Clone
GK1.5
Conjugate
Functional Grade
Gene
CD4
Gene Alias
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen
Host Species
Rat
Quantity
50 mg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- The BMA12 monoclonal antibody reacts with mouse CD100, also known as Sema4D
- Sema4D/CD100 is a 150kDa transmembrane protein expressed constitutively on T cells and is involved in the activation of B cells through its interaction with CD72
- Interaction of these two proteins diminishes the negative signaling normally effected by CD72
- CD100 is already expressed strongly on resting T cells and somewhat weakly on B cells, but activation upregulates expression on both cell types
- Antigen expression has been reported in Spleen, thymus and l The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV
- CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells
- At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues
- CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck
- It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system
- Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].