Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), Functional Grade, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 16-593-195-Each-of-1 | In Stock | ₹ 2,61,660.00 |
16-593-195 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 2,61,660.00
GST (18%): ₹ 47,098.80
Total Price: ₹ 3,08,758.80
Antigen
Ly-6G/Ly-6C
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative; pH 7.2
Gene Accession No.
P0CW02, P0CW03, P35461
Gene Symbols
Ly6c1, Ly6c2, Ly6g
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100041546, 17067, 546644
Content And Storage
4° C
Form
Liquid
Applications
Flow Cytometry, Functional Assay
Clone
RB6-8C5
Conjugate
Functional Grade
Gene
Ly6g
Gene Alias
AA682074; AA959465; Gr1; Gr-1; Granulocyte Marker; Ly6c; Ly-6C; Ly-6C.2; Ly6c1; Ly-6C1; Ly6c2; Ly-6C2; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6 complex, locus C1; lymphocyte antigen 6 complex, locus C2; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6C precursor (Ly-6C); lymphocyte antigen 6C1; Lymphocyte antigen 6C2; lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN
Host Species
Rat
Quantity
10 mg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2b κ
Related Products
Description
- The RB6-8C5 MAb reacts with mouse Ly-6G, a 21-25 kDa protein also known as the myeloid differentiation antigen Gr-1
- A GPI-linked protein, Gr-1 is expressed by the myeloid lineage in a developmentally regulated manner in the bone marrow
- While monocytes only express Gr-1 transiently during their bone marrow development, the expression of Gr-1 on bone marrow granulocytes as well as on peripheral neutrophils is a good marker for these populations
- eBioscience testing indicates that in the bone marrow and lysed whole blood, the antibody clone RB6-8C5 also stains cells that express the highest levels of Ly6c (as defined by staining with antibody clone HK1.4)
- It is recommended that 1A8-Ly6G (cat
- 9668) be used when looking at Ly-6G specific targets
- Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm
- They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments
- In common parlance, the term polymorphonuclear leukocyte often refers specifically to neutrophil granulocytes, the most abundant of the granulocytes
- Granulocytes or PMN are released from the bone marrow by the regulatory complement proteins.