IL-17AF Monoclonal Antibody (1402nAF), Functional Grade, eBioscience™, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 16-917-238-Each-of-1 | In Stock | ₹ 2,54,540.00 |
16-917-238 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 2,54,540.00
GST (18%): ₹ 45,817.20
Total Price: ₹ 3,00,357.20
Antigen
IL-17AF
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with no preservative; pH 7.2
Gene Accession No.
Q62386, Q7TNI7
Gene Symbols
Il17a, Il17f
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16171, 257630
Content And Storage
4° C, do not freeze
Form
Liquid
Applications
Functional Assay, Neutralization
Clone
1402nAF
Conjugate
Functional Grade
Gene
Il17a
Gene Alias
C87042; CANDF6; Ctla8; CTLA-8; cytokine ML-1; Cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; il 17; IL17; IL-17; Il17a; IL-17A; IL17F; IL-17F; ILN; Interleukin; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A; interleukin 17F; interleukin-17A; Interleukin-17F; ML1; ML-1
Host Species
Rat
Quantity
5 mg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a κ
Related Products
Description
- Description: The 1402nAF monoclonal antibody reacts with mouse interleukin (IL)-17AF heterodimer
- This antibody specifically reacts with this heterodimer and has no reactivity for IL-17A or IL-17F homodimers
- Applications Reported: This 1402nAF antibody has been reported for use as a neutralization antibody of IL-17AF biological activity
- Applications Tested: The Functional Grade purified format of the 1402nAF antibody has been tested for neutralization of IL-17AF biological activity
- Storage and handling: Use in a sterile environment
- Filtration: 0.2 μm post-manufacturing filtered
- Purity: Greater than 90%, as determined by SDS-PAGE
- Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay
- Aggregation: Less than 10%, as determined by HPLC
- IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells
- Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF
- Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis.