20-891-050UL
MilliporeSigma™ anti-Calreticulin (405-417), Polyclonal
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 20-891-050UL-Each-of-1 | In Stock | ₹ 39,245.44 |
20-891-050UL - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,245.44
GST (18%): ₹ 7,064.179
Total Price: ₹ 46,309.619
Antigen
Calreticulin (405-417)
Classification
Polyclonal
Formulation
In PBS, 50% glycerol, pH 7.2.
Immunogen
a synthetic peptide [(C)EEEDVPGQAKDEL] corresponding to amino acids 405-417 of human calreticulin, conjugated to KLH
Regulatory Status
RUO
Test Specificity
Recognizes the ∽63kDa calreticulin protein in heat-shocked HeLa cells.
Content And Storage
−20°C
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation
Conjugate
Unconjugated
Host Species
Rabbit
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Bovine, Canine, Hamster, Human, Monkey, Mouse, Porcine, Rat
Form
Purified
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Description
- Specifically detects Calreticulin (405-417) Clone: in Bovine, Canine, Hamster, Human, Monkey, Mouse, Porcine, Rat samples, and it is validated for Immunocytochemistry, Immunohistochemistry, Immunoprecipitation Calreticulin is a calcium binding protein found primarily in the ER and the sarcoplasmic reticulum, although it also has been detected in the nucleus and nuclear envelope
- It has the conserved KDEL sequence at its C-terminus for retention in the ER
- Calreticulin, which contains both high and low affinity calcium binding sites, is involved in calcium storage and regulation
- The calcium binding at the C-terminus of calreticulin has been postulated to be involved with regulating the interaction of KDEL proteins with the KDEL receptor
- Calreticulin also acts as a molecular chaperone for protein folding, in concert with Grp78 and Grp94.