200004009

CD69 Monoclonal Antibody (H1.2F3), Brilliant Ultra Violet™ 496, eBioscience™, Invitrogen™

Armenian Hamster Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD69

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias

5830438K24Rik; Activation inducer molecule; activation inducer molecule (AIM/CD69); AI452015; AIM; BL-AC/P26; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CD69 molecule; CLEC2C; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; EA1; early activation antigen CD69; early lymphocyte activation antigen; early T-cell activation antigen p60; GP32/28; leukocyte surface antigen Leu-23; MLR-3; VEA; Very Early Activation Antigen

Gene Symbols

CD69

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

CD69

Clone

H1.2F3

Applications

Flow Cytometry

Conjugate

Brilliant Ultraviolet 496

Host Species

Armenian Hamster

Target Species

Mouse

Gene Accession No.

P37217

Gene ID (Entrez)

12515

Isotype

IgG

Purification Method

Affinity chromatography

Product Type

Antibody

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Description

  • CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions
  • CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets
  • In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction
  • Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation
  • Furthermore, the protein may act to transmit signals in natural killer cells and platelets
  • Alternative splicing results in multiple transcript variants of CD69
  • Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.